High activity and low toxicity of a novel CD71-targeting nanotherapeutic named The-0504 on preclinical models of several human aggressive tumors

BACKGROUND: Ferritin receptor (CD71) is an example of a very attractive cancer target, since it is highly expressed in virtually all tumor types, including metastatic loci. However, this target can be considered to be inaccessible to conventional target therapies, due to its presence in many healthy...

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Detalles Bibliográficos
Autores principales: Falvo, Elisabetta, Damiani, Verena, Conti, Giamaica, Boschi, Federico, Messana, Katia, Giacomini, Patrizio, Milella, Michele, De Laurenzi, Vincenzo, Morea, Veronica, Sala, Gianluca, Fracasso, Giulio, Ceci, Pierpaolo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7877078/
https://www.ncbi.nlm.nih.gov/pubmed/33568214
http://dx.doi.org/10.1186/s13046-021-01851-8

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7877078/
https://www.ncbi.nlm.nih.gov/pubmed/33568214
http://dx.doi.org/10.1186/s13046-021-01851-8

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