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Patient-derived non-small cell lung cancer xenograft mirrors complex tumor heterogeneity
OBJECTIVE: Patient-derived xenograft (PDX) models have shown great promise in preclinical and translational applications, but their consistency with primary tumors in phenotypic, genetic, and pharmacodynamic heterogeneity has not been well-studied. This study aimed to establish a PDX repository for...
Autores principales: | , , , , , , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Compuscript
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7877179/ https://www.ncbi.nlm.nih.gov/pubmed/33628593 http://dx.doi.org/10.20892/j.issn.2095-3941.2020.0012 |