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Patient-derived non-small cell lung cancer xenograft mirrors complex tumor heterogeneity

OBJECTIVE: Patient-derived xenograft (PDX) models have shown great promise in preclinical and translational applications, but their consistency with primary tumors in phenotypic, genetic, and pharmacodynamic heterogeneity has not been well-studied. This study aimed to establish a PDX repository for...

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Detalles Bibliográficos
Autores principales: Chen, Xuanming, Shen, Cheng, Wei, Zhe, Zhang, Rui, Wang, Yongsheng, Jiang, Lili, Chen, Ke, Qiu, Shuang, Zhang, Yuanli, Zhang, Ting, Chen, Bin, Xu, Yanjun, Feng, Qiyi, Huang, Jinxing, Zhong, Zhihui, Li, Hongxia, Che, Guowei, Xiao, Kai
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Compuscript 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7877179/
https://www.ncbi.nlm.nih.gov/pubmed/33628593
http://dx.doi.org/10.20892/j.issn.2095-3941.2020.0012