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The IL-33/ST2 axis affects tumor growth by regulating mitophagy in macrophages and reprogramming their polarization
OBJECTIVE: Macrophages are a major component of the tumor microenvironment. M1 macrophages secrete pro-inflammatory factors that inhibit tumor growth and development, whereas tumor-associated macrophages (TAMs) mainly exhibit an M2 phenotype. Our previous studies have shown that the interleukin-33/S...
Autores principales: | , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Compuscript
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7877183/ https://www.ncbi.nlm.nih.gov/pubmed/33628592 http://dx.doi.org/10.20892/j.issn.2095-3941.2020.0211 |