The IL-33/ST2 axis affects tumor growth by regulating mitophagy in macrophages and reprogramming their polarization

OBJECTIVE: Macrophages are a major component of the tumor microenvironment. M1 macrophages secrete pro-inflammatory factors that inhibit tumor growth and development, whereas tumor-associated macrophages (TAMs) mainly exhibit an M2 phenotype. Our previous studies have shown that the interleukin-33/S...

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Detalles Bibliográficos
Autores principales: Xu, Huadan, Li, Dong, Ma, Jiaoyan, Zhao, Yuanxin, Xu, Long, Tian, Rui, Liu, Yanan, Sun, Liankun, Su, Jing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Compuscript 2021
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7877183/
https://www.ncbi.nlm.nih.gov/pubmed/33628592
http://dx.doi.org/10.20892/j.issn.2095-3941.2020.0211

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