The cancer-testis gene, MEIOB, sensitizes triple-negative breast cancer to PARP1 inhibitors by inducing homologous recombination deficiency

OBJECTIVE: The newly defined cancer-testis (CT) gene, MEIOB, was previously found to play key roles in DNA double-strand break (DSB) repair. In this study, we aimed to investigate the effects and mechanisms of MEIOB in the carcinogenesis of triple-negative breast cancers (TNBCs). METHODS: The Cancer...

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Detalles Bibliográficos
Autores principales: Gu, Yayun, Wang, Cheng, Zhu, Rongxuan, Yang, Jianshui, Yuan, Wenwen, Zhu, Yanhui, Zhou, Yan, Qin, Na, Shen, Hongbing, Ma, Hongxia, Wang, Hongxia, Liu, Xiaoan, Hu, Zhibin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Compuscript 2021
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7877187/
https://www.ncbi.nlm.nih.gov/pubmed/33628586
http://dx.doi.org/10.20892/j.issn.2095-3941.2020.0071

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7877187/
https://www.ncbi.nlm.nih.gov/pubmed/33628586
http://dx.doi.org/10.20892/j.issn.2095-3941.2020.0071

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