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Self-Amplifying Pestivirus Replicon RNA Encoding Influenza Virus Nucleoprotein and Hemagglutinin Promote Humoral and Cellular Immune Responses in Pigs

Self-amplifying replicon RNA (RepRNA) promotes expansion of mRNA templates encoding genes of interest through their replicative nature, thus providing increased antigen payloads. RepRNA derived from the non-cytopathogenic classical swine fever virus (CSFV) targets monocytes and dendritic cells (DCs)...

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Detalles Bibliográficos
Autores principales: Démoulins, Thomas, Ruggli, Nicolas, Gerber, Markus, Thomann-Harwood, Lisa J., Ebensen, Thomas, Schulze, Kai, Guzmán, Carlos A., McCullough, Kenneth C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7877248/
https://www.ncbi.nlm.nih.gov/pubmed/33584723
http://dx.doi.org/10.3389/fimmu.2020.622385