Class I histone deacetylase inhibition promotes CD8 T cell activation in ovarian cancer

OBJECTIVE: Patients with epithelial ovarian cancer (EOC) typically present with late‐stage disease, posing a significant challenge to treatment. Although taxane and platinum‐based chemotherapy plus surgical debulking are initially effective, EOC is marked by frequent recurrence with resistant diseas...

Descripción completa

Detalles Bibliográficos
Autores principales: McCaw, Tyler R., Goel, Nidhi, Brooke, Dewey J., Katre, Ashwini A., Londoño, Angelina I., Smith, Haller J., Randall, Troy D., Arend, Rebecca C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2020
Materias:
Cancer Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7877343/
https://www.ncbi.nlm.nih.gov/pubmed/33369199
http://dx.doi.org/10.1002/cam4.3337

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7877343/
https://www.ncbi.nlm.nih.gov/pubmed/33369199
http://dx.doi.org/10.1002/cam4.3337

Ejemplares similares