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Effects of L-DOPA on Gene Expression in the Frontal Cortex of Rats with Unilateral Lesions of Midbrain Dopaminergic Neurons

The development of Parkinson’s disease (PD) causes dysfunction of the frontal cortex, which contributes to the hallmark motor symptoms and is regarded as one of the primary causes of the affective and cognitive impairments observed in PD. Treatment with L-3,4-dihydroxyphenylalanine (L-DOPA) alleviat...

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Detalles Bibliográficos
Autores principales: Radlicka, Anna, Kamińska, Kinga, Borczyk, Malgorzata, Piechota, Marcin, Korostyński, Michał, Pera, Joanna, Lorenc-Koci, Elżbieta, Rodriguez Parkitna, Jan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Society for Neuroscience 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7877460/
https://www.ncbi.nlm.nih.gov/pubmed/33257528
http://dx.doi.org/10.1523/ENEURO.0234-20.2020