Lytic Cell Death in Specific Microglial Subsets Is Required for Preventing Atypical Behavior in Mice

Microglial cells are known to contribute to brain development and behaviors, but the mechanisms behind such functions are not fully understood. Here, we show that mice deficient in inflammasome regulators, including caspase-1 (Casp1), NLR family pyrin domain containing 3 (Nlrp3), IL-1 receptor (Il-1...

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Detalles Bibliográficos
Autores principales: Chuang, Hsiu-Chun, Nichols, Eva K., Rauch, Isabella, Chang, Wei-Cheng, Lin, Patrick M., Misra, Rhea, Kitaoka, Maiko, Vance, Russell E., Saijo, Kaoru
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Society for Neuroscience 2021
Materias:
Research Article: New Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7877467/
https://www.ncbi.nlm.nih.gov/pubmed/33414187
http://dx.doi.org/10.1523/ENEURO.0342-20.2020

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7877467/
https://www.ncbi.nlm.nih.gov/pubmed/33414187
http://dx.doi.org/10.1523/ENEURO.0342-20.2020

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