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SRF Is Required for Maintenance of Astrocytes in Non-Reactive State in the Mammalian Brain

Astrocytes play several critical roles in the normal functioning of the mammalian brain, including ion homeostasis, synapse formation, and synaptic plasticity. Following injury and infection or in the setting of neurodegeneration, astrocytes become hypertrophic and reactive, a process termed astrogl...

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Detalles Bibliográficos
Autores principales: Jain, Monika, Das, Soumen, Lu, Paul P. Y., Virmani, Garima, Soman, Sumitha, Thumu, Surya Chandra Rao, Gutmann, David H., Ramanan, Narendrakumar
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Society for Neuroscience 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7877468/
https://www.ncbi.nlm.nih.gov/pubmed/33441399
http://dx.doi.org/10.1523/ENEURO.0447-19.2020