Excessive Formation and Stabilization of Dendritic Spine Clusters in the MECP2-Duplication Syndrome Mouse Model of Autism

Autism-associated genetic mutations may perturb the balance between stability and plasticity of synaptic connections in the brain. Here, we report an increase in the formation and stabilization of dendritic spines in the cerebral cortex of the mouse model of MECP2-duplication syndrome, a high-penetr...

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Detalles Bibliográficos
Autores principales: Ash, Ryan Thomas, Park, Jiyoung, Suter, Bernhard, Zoghbi, Huda Yaya, Smirnakis, Stelios Manolis
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Society for Neuroscience 2021
Materias:
Research Article: New Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7877475/
https://www.ncbi.nlm.nih.gov/pubmed/33168618
http://dx.doi.org/10.1523/ENEURO.0282-20.2020

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7877475/
https://www.ncbi.nlm.nih.gov/pubmed/33168618
http://dx.doi.org/10.1523/ENEURO.0282-20.2020

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