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Excessive Formation and Stabilization of Dendritic Spine Clusters in the MECP2-Duplication Syndrome Mouse Model of Autism
Autism-associated genetic mutations may perturb the balance between stability and plasticity of synaptic connections in the brain. Here, we report an increase in the formation and stabilization of dendritic spines in the cerebral cortex of the mouse model of MECP2-duplication syndrome, a high-penetr...
Autores principales: | Ash, Ryan Thomas, Park, Jiyoung, Suter, Bernhard, Zoghbi, Huda Yaya, Smirnakis, Stelios Manolis |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Society for Neuroscience
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7877475/ https://www.ncbi.nlm.nih.gov/pubmed/33168618 http://dx.doi.org/10.1523/ENEURO.0282-20.2020 |
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