Rapid generation of durable B cell memory to SARS-CoV-2 spike and nucleocapsid proteins in COVID-19 and convalescence

Lasting immunity following SARS-CoV-2 infection is questioned because serum antibodies decline in convalescence. However, functional immunity is mediated by long-lived memory T and B (Bmem) cells. Therefore, we generated fluorescently-labeled tetramers of the spike receptor binding domain (RBD) and...

Descripción completa

Detalles Bibliográficos
Autores principales: Hartley, Gemma E., Edwards, Emily S.J., Aui, Pei M., Varese, Nirupama, Stojanovic, Stephanie, McMahon, James, Peleg, Anton Y., Boo, Irene, Drummer, Heidi E., Hogarth, P. Mark, O’Hehir, Robyn E., van Zelm, Menno C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for the Advancement of Science 2020
Materias:
Reports
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7877496/
https://www.ncbi.nlm.nih.gov/pubmed/33443036
http://dx.doi.org/10.1126/sciimmunol.abf8891

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7877496/
https://www.ncbi.nlm.nih.gov/pubmed/33443036
http://dx.doi.org/10.1126/sciimmunol.abf8891

Ejemplares similares