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Rapid generation of durable B cell memory to SARS-CoV-2 spike and nucleocapsid proteins in COVID-19 and convalescence
Lasting immunity following SARS-CoV-2 infection is questioned because serum antibodies decline in convalescence. However, functional immunity is mediated by long-lived memory T and B (Bmem) cells. Therefore, we generated fluorescently-labeled tetramers of the spike receptor binding domain (RBD) and...
Autores principales: | Hartley, Gemma E., Edwards, Emily S.J., Aui, Pei M., Varese, Nirupama, Stojanovic, Stephanie, McMahon, James, Peleg, Anton Y., Boo, Irene, Drummer, Heidi E., Hogarth, P. Mark, O’Hehir, Robyn E., van Zelm, Menno C. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Association for the Advancement of Science
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7877496/ https://www.ncbi.nlm.nih.gov/pubmed/33443036 http://dx.doi.org/10.1126/sciimmunol.abf8891 |
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