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Genome-wide transcriptome and translatome analyses reveal the role of protein extension and domestication in liver cancer oncogenesis

One gene could be transcribed to different RNA isoforms, and then produce various forms of protein sequences. This mechanism largely diversifies the cellular pool and allows natural selection to select from a wider range of substrates. In the cancer field, the isoform switches between tumor and norm...

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Detalles Bibliográficos
Autores principales: Wang, Nima, Wang, Dalei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7877501/
https://www.ncbi.nlm.nih.gov/pubmed/33575838
http://dx.doi.org/10.1007/s00438-021-01766-1