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Genome-wide transcriptome and translatome analyses reveal the role of protein extension and domestication in liver cancer oncogenesis
One gene could be transcribed to different RNA isoforms, and then produce various forms of protein sequences. This mechanism largely diversifies the cellular pool and allows natural selection to select from a wider range of substrates. In the cancer field, the isoform switches between tumor and norm...
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer Berlin Heidelberg
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7877501/ https://www.ncbi.nlm.nih.gov/pubmed/33575838 http://dx.doi.org/10.1007/s00438-021-01766-1 |