Assessment of dynamic cardiac repolarization and contractility in patients with hypertrophic cardiomyopathy

AIMS: Arrhythmia mechanisms in hypertrophic cardiomyopathy remain uncertain. Preclinical models suggest hypertrophic cardiomyopathy-linked mutations perturb sarcomere length-dependent activation, alter cardiac repolarization in rate-dependent fashion and potentiate triggered electrical activity. Thi...

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Detalles Bibliográficos
Autores principales: Radbill, Andrew E., Lei, Lucy Y., Paranjape, Sachin Y., Blackwell, Daniel J., Abraham, Robert L., Chew, Derek S., Raj, Satish R., Knollmann, Björn C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2021
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7877626/
https://www.ncbi.nlm.nih.gov/pubmed/33571287
http://dx.doi.org/10.1371/journal.pone.0246768

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7877626/
https://www.ncbi.nlm.nih.gov/pubmed/33571287
http://dx.doi.org/10.1371/journal.pone.0246768

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