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A novel ROCK inhibitor: off-target effects of metformin

In drug discovery, most small molecules cannot cross many stages, only a few can become drug candidates. Once the drug molecule is approved and marketed, nontarget effects that are not easily distinguishable from the actual target of the drugs might be evaluated. This situation restricts the treatme...

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Detalles Bibliográficos
Autores principales: ÖZDEMİR, Aysun, ARK, Mustafa
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Scientific and Technological Research Council of Turkey 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7877715/
https://www.ncbi.nlm.nih.gov/pubmed/33597820
http://dx.doi.org/10.3906/biy-2004-12