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Inhibition of Amyloid β-Induced Lipid Membrane Permeation and Amyloid β Aggregation by K162
[Image: see text] Alzheimer’s disease (AD) is characterized by progressive neurodegeneration associated with amyloid β (Aβ) peptide aggregation. The aggregation of Aβ monomers (AβMs) leads to the formation of Aβ oligomers (AβOs), the neurotoxic Aβ form, capable of permeating the cell membrane. Here,...
Autores principales: | , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Chemical Society
2021
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7877724/ https://www.ncbi.nlm.nih.gov/pubmed/33478212 http://dx.doi.org/10.1021/acschemneuro.0c00754 |