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Inhibition of Amyloid β-Induced Lipid Membrane Permeation and Amyloid β Aggregation by K162

[Image: see text] Alzheimer’s disease (AD) is characterized by progressive neurodegeneration associated with amyloid β (Aβ) peptide aggregation. The aggregation of Aβ monomers (AβMs) leads to the formation of Aβ oligomers (AβOs), the neurotoxic Aβ form, capable of permeating the cell membrane. Here,...

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Detalles Bibliográficos
Autores principales: Mrdenovic, Dusan, Zarzycki, Piotr, Majewska, Marta, Pieta, Izabela S., Nowakowski, Robert, Kutner, Wlodzimierz, Lipkowski, Jacek, Pieta, Piotr
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2021
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7877724/
https://www.ncbi.nlm.nih.gov/pubmed/33478212
http://dx.doi.org/10.1021/acschemneuro.0c00754

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