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Occurrence of Morpholine in Central Nervous System Drug Discovery

[Image: see text] Developing drugs for the central nervous system (CNS) requires fine chemical modifications, as a strict balance between size and lipophilicity is necessary to improve the permeability through the blood-brain barrier (BBB). In this context, morpholine and its analogues represent val...

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Detalles Bibliográficos
Autores principales: Lenci, Elena, Calugi, Lorenzo, Trabocchi, Andrea
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2021
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7877733/
https://www.ncbi.nlm.nih.gov/pubmed/33459557
http://dx.doi.org/10.1021/acschemneuro.0c00729