Conserved amino acids in the region connecting membrane spanning domain 1 to nucleotide binding domain 1 are essential for expression of the MRP1 (ABCC1) transporter

Multidrug resistance protein 1 (MRP1) (gene symbol ABCC1) is an ATP-binding cassette (ABC) transporter which effluxes xeno- and endobiotic organic anions including estradiol glucuronide and the pro-inflammatory leukotriene C(4). MRP1 also confers multidrug resistance by reducing intracellular drug a...

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Detalles Bibliográficos
Autores principales: Smith, Emma E., Conseil, Gwenaëlle, Cole, Susan P. C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2021
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7877750/
https://www.ncbi.nlm.nih.gov/pubmed/33571281
http://dx.doi.org/10.1371/journal.pone.0246727

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7877750/
https://www.ncbi.nlm.nih.gov/pubmed/33571281
http://dx.doi.org/10.1371/journal.pone.0246727

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