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Tripartite Motif 22 (TRIM22) protein restricts herpes simplex virus 1 by epigenetic silencing of viral immediate-early genes

Intrinsic resistance is a crucial line of defense against virus infections, and members of the Tripartite Ring Interaction Motif (TRIM) family of proteins are major players in this system, such as cytoplasmic TRIM5α or nuclear promyelocytic leukemia (PML/TRIM19) protein. Previous reports on the anti...

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Detalles Bibliográficos
Autores principales: Reddi, Tejaswini S., Merkl, Philipp E., Lim, So-Yon, Letvin, Norman L., Knipe, David M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7877759/
https://www.ncbi.nlm.nih.gov/pubmed/33524065
http://dx.doi.org/10.1371/journal.ppat.1009281