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Directed attenuation to enhance vaccine immunity

Many viral infections can be prevented by immunizing with live, attenuated vaccines. Early methods of attenuation were hit-and-miss, now much improved by genetic engineering. However, even current methods operate on the principle of genetic harm, reducing the virus’s ability to grow. Reduced viral g...

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Detalles Bibliográficos
Autores principales: Antia, Rustom, Ahmed, Hasan, Bull, James J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7877766/
https://www.ncbi.nlm.nih.gov/pubmed/33524036
http://dx.doi.org/10.1371/journal.pcbi.1008602