Cargando…
Directed attenuation to enhance vaccine immunity
Many viral infections can be prevented by immunizing with live, attenuated vaccines. Early methods of attenuation were hit-and-miss, now much improved by genetic engineering. However, even current methods operate on the principle of genetic harm, reducing the virus’s ability to grow. Reduced viral g...
Autores principales: | Antia, Rustom, Ahmed, Hasan, Bull, James J. |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2021
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7877766/ https://www.ncbi.nlm.nih.gov/pubmed/33524036 http://dx.doi.org/10.1371/journal.pcbi.1008602 |
Ejemplares similares
-
Which ‘imperfect vaccines’ encourage the evolution of higher virulence?
por: Bull, James J, et al.
Publicado: (2022) -
Recombinant vector vaccine evolution
por: Bull, James J., et al.
Publicado: (2019) -
Successes and Failures of the Live-attenuated Influenza Vaccine: Can We Do Better?
por: Matrajt, Laura, et al.
Publicado: (2020) -
Heterogeneity and longevity of antibody memory to viruses and vaccines
por: Antia, Alice, et al.
Publicado: (2018) -
Modeling suggests that multiple immunizations or infections will reveal the benefits of updating SARS-CoV-2 vaccines
por: Desikan, Rajat, et al.
Publicado: (2022)