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Divergent features of the coenzyme Q:cytochrome c oxidoreductase complex in Toxoplasma gondii parasites

The mitochondrion is critical for the survival of apicomplexan parasites. Several major anti-parasitic drugs, such as atovaquone and endochin-like quinolones, act through inhibition of the mitochondrial electron transport chain at the coenzyme Q:cytochrome c oxidoreductase complex (Complex III). Des...

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Detalles Bibliográficos
Autores principales: Hayward, Jenni A., Rajendran, Esther, Zwahlen, Soraya M., Faou, Pierre, van Dooren, Giel G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7877769/
https://www.ncbi.nlm.nih.gov/pubmed/33524071
http://dx.doi.org/10.1371/journal.ppat.1009211