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Design principles for the glycoprotein quality control pathway

Newly-translated glycoproteins in the endoplasmic reticulum (ER) often undergo cycles of chaperone binding and release in order to assist in folding. Quality control is required to distinguish between proteins that have completed native folding, those that have yet to fold, and those that have misfo...

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Detalles Bibliográficos
Autores principales: Brown, Aidan I., Koslover, Elena F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7877790/
https://www.ncbi.nlm.nih.gov/pubmed/33524026
http://dx.doi.org/10.1371/journal.pcbi.1008654