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Population Pharmacokinetics of Candesartan in Patients with Chronic Heart Failure

Heart failure (HF) causes pathological changes in multiple organs, thus affecting the pharmacokinetics (PK) of drugs. The aim of this study was to investigate the PK of candesartan in patients with HF while examining significant covariates and their related impact on estimated clearance using a popu...

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Detalles Bibliográficos
Autores principales: Kassem, Imad, Sanche, Steven, Li, Jun, Bonnefois, Guillaume, Dubé, Marie‐Pierre, Rouleau, Jean‐Lucien, Tardif, Jean‐Claude, White, Michel, Turgeon, Jacques, Nekka, Fahima, de Denus, Simon
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7877833/
https://www.ncbi.nlm.nih.gov/pubmed/32702160
http://dx.doi.org/10.1111/cts.12842