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An Investigation of the Metabolism and Excretion of KD101 and Its Interindividual Differences: A Microtracing Mass Balance Study in Humans

The absorption, metabolism, and excretion (AME) profiles of KD101, currently under clinical development to treat obesity, were assessed in humans using accelerator mass spectrometry (AMS) after a single oral administration of KD101 at 400 mg and a microdose of (14)C‐KD101 at ~ 35.2 μg with a total r...

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Detalles Bibliográficos
Autores principales: Kim, Anhye, Dueker, Stephen R., Hwang, Jun Gi, Yoon, Jangsoo, Lee, Sang‐Won, Lee, Hye Suk, Yu, Byung‐Yong, Yu, Kyung‐Sang, Lee, Howard
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7877834/
https://www.ncbi.nlm.nih.gov/pubmed/33460293
http://dx.doi.org/10.1111/cts.12848