Quantitative Clinical Pharmacology of T‐Cell Engaging Bispecifics: Current Perspectives and Opportunities

T‐cell directing/engaging bispecifics (TDBs) enable a powerful mode of action by activating T‐cells through the creation of artificial immune synapses. Their pharmacological response involves the dynamic inter‐relationships among T‐cells, tumor cells, and TDBs. This results in complex and challengin...

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Detalles Bibliográficos
Autores principales: Morcos, Peter N., Li, Junyi, Hosseini, Iraj, Li, Chi‐Chung
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2020
Materias:
Reviews
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7877841/
https://www.ncbi.nlm.nih.gov/pubmed/32882099
http://dx.doi.org/10.1111/cts.12877

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7877841/
https://www.ncbi.nlm.nih.gov/pubmed/32882099
http://dx.doi.org/10.1111/cts.12877

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