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Substantially Increased Plasma Coproporphyrin‐I Concentrations Associated With OATP1B1*15 Allele in Japanese General Population

Coproporphyrin‐I (CP‐I) in plasma is a sensitive and specific endogenous probe for phenotyping organic anion transporting polypeptides 1B (OATP1B, encoded by SLCO1B). A few small‐scale studies suggested that plasma CP‐I concentration is affected by OATP1B1 polymorphism, but detailed studies are lack...

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Detalles Bibliográficos
Autores principales: Suzuki, Yosuke, Sasamoto, Yuri, Koyama, Teruhide, Yoshijima, Chisato, Nakatochi, Masahiro, Kubo, Michiaki, Momozawa, Yukihide, Uehara, Ritei, Ohno, Keiko
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7877856/
https://www.ncbi.nlm.nih.gov/pubmed/32961019
http://dx.doi.org/10.1111/cts.12889