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A Dynamic Quantitative Systems Pharmacology Model of Inflammatory Bowel Disease: Part 2 – Application to Current Therapies in Crohn’s Disease

Inflammatory bowel disease (IBD) is a heterogeneic disease with a variety of treatments targeting different mechanisms. A multistate, mechanistic, mathematical model of IBD was developed in part 1 of this two‐part article series. In this paper, application of the model to predict response of key cli...

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Detalles Bibliográficos
Autores principales: Rogers, Katharine V., Martin, Steven W., Bhattacharya, Indranil, Singh, Ravi Shankar Prasad, Nayak, Satyaprakash
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7877864/
https://www.ncbi.nlm.nih.gov/pubmed/32822115
http://dx.doi.org/10.1111/cts.12850