DNA Methylation‐Based Epigenetic Repression of SLC22A4 Promotes Resistance to Cytarabine in Acute Myeloid Leukemia

Reduced expression of the uptake transporter, OCTN1 (SLC22A4), has been reported as a strong predictor of poor event‐free and overall survival in multiple cohorts of patients with acute myeloid leukemia (AML) receiving the cytidine nucleoside analog, cytarabine (Ara‐C). To further understand the mec...

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Detalles Bibliográficos
Autores principales: Buelow, Daelynn R., Anderson, Jason T., Pounds, Stanley B., Shi, Lei, Lamba, Jatinder K., Hu, Shuiying, Gibson, Alice A., Goodwin, Emily A., Sparreboom, Alex, Baker, Sharyn D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2020
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7877866/
https://www.ncbi.nlm.nih.gov/pubmed/32905646
http://dx.doi.org/10.1111/cts.12861

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7877866/
https://www.ncbi.nlm.nih.gov/pubmed/32905646
http://dx.doi.org/10.1111/cts.12861

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