Charge-driven condensation of RNA and proteins suggests broad role of phase separation in cytoplasmic environments

Phase separation processes are increasingly being recognized as important organizing mechanisms of biological macromolecules in cellular environments. Well-established drivers of phase separation are multi-valency and intrinsic disorder. Here, we show that globular macromolecules may condense simply...

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Detalles Bibliográficos
Autores principales: Dutagaci, Bercem, Nawrocki, Grzegorz, Goodluck, Joyce, Ashkarran, Ali Akbar, Hoogstraten, Charles G, Lapidus, Lisa J, Feig, Michael
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2021
Materias:
Physics of Living Systems
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7877912/
https://www.ncbi.nlm.nih.gov/pubmed/33496264
http://dx.doi.org/10.7554/eLife.64004

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7877912/
https://www.ncbi.nlm.nih.gov/pubmed/33496264
http://dx.doi.org/10.7554/eLife.64004

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