Cargando…
Charge-driven condensation of RNA and proteins suggests broad role of phase separation in cytoplasmic environments
Phase separation processes are increasingly being recognized as important organizing mechanisms of biological macromolecules in cellular environments. Well-established drivers of phase separation are multi-valency and intrinsic disorder. Here, we show that globular macromolecules may condense simply...
Autores principales: | Dutagaci, Bercem, Nawrocki, Grzegorz, Goodluck, Joyce, Ashkarran, Ali Akbar, Hoogstraten, Charles G, Lapidus, Lisa J, Feig, Michael |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
eLife Sciences Publications, Ltd
2021
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7877912/ https://www.ncbi.nlm.nih.gov/pubmed/33496264 http://dx.doi.org/10.7554/eLife.64004 |
Ejemplares similares
-
Restricting the sizes of condensates
por: Dar, Furqan, et al.
Publicado: (2020) -
Condensation tendency and planar isotropic actin gradient induce radial alignment in confined monolayers
por: Xie, Tianfa, et al.
Publicado: (2021) -
Protein compactness and interaction valency define the architecture of a biomolecular condensate across scales
por: Polyansky, Anton A, et al.
Publicado: (2023) -
Mesoscale phase separation of chromatin in the nucleus
por: Bajpai, Gaurav, et al.
Publicado: (2021) -
Decoding the physical principles of two-component biomolecular phase separation
por: Zhang, Yaojun, et al.
Publicado: (2021)