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Opposing Wnt signals regulate cervical squamocolumnar homeostasis and emergence of metaplasia

The transition zones of the squamous and columnar epithelia constitute hotspots for the emergence of cancer, often preceded by metaplasia, in which one epithelial type is replaced by another. It remains unclear how the epithelial spatial organization is maintained and how the transition zone niche i...

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Detalles Bibliográficos
Autores principales: Chumduri, Cindrilla, Gurumurthy, Rajendra Kumar, Berger, Hilmar, Dietrich, Oliver, Kumar, Naveen, Koster, Stefanie, Brinkmann, Volker, Hoffmann, Kirstin, Drabkina, Marina, Arampatzi, Panagiota, Son, Dajung, Klemm, Uwe, Mollenkopf, Hans-Joachim, Herbst, Hermann, Mangler, Mandy, Vogel, Jörg, Saliba, Antoine-Emmanuel, Meyer, Thomas F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7878191/
https://www.ncbi.nlm.nih.gov/pubmed/33462395
http://dx.doi.org/10.1038/s41556-020-00619-0