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Opposing Wnt signals regulate cervical squamocolumnar homeostasis and emergence of metaplasia
The transition zones of the squamous and columnar epithelia constitute hotspots for the emergence of cancer, often preceded by metaplasia, in which one epithelial type is replaced by another. It remains unclear how the epithelial spatial organization is maintained and how the transition zone niche i...
Autores principales: | Chumduri, Cindrilla, Gurumurthy, Rajendra Kumar, Berger, Hilmar, Dietrich, Oliver, Kumar, Naveen, Koster, Stefanie, Brinkmann, Volker, Hoffmann, Kirstin, Drabkina, Marina, Arampatzi, Panagiota, Son, Dajung, Klemm, Uwe, Mollenkopf, Hans-Joachim, Herbst, Hermann, Mangler, Mandy, Vogel, Jörg, Saliba, Antoine-Emmanuel, Meyer, Thomas F. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7878191/ https://www.ncbi.nlm.nih.gov/pubmed/33462395 http://dx.doi.org/10.1038/s41556-020-00619-0 |
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