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Single-cell metabolic profiling of human cytotoxic T cells

Cellular metabolism regulates immune cell activation, differentiation and effector functions but current metabolic approaches lack single-cell resolution and simultaneous characterization of cellular phenotype. Here, we developed an approach to characterize the metabolic regulome of single cells tog...

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Detalles Bibliográficos
Autores principales: Hartmann, Felix J., Mrdjen, Dunja, McCaffrey, Erin, Glass, David R., Greenwald, Noah F., Bharadwaj, Anusha, Khair, Zumana, Verberk, Sanne G.S., Baranski, Alex, Baskar, Reema, Graf, William, Van Valen, David, den Bossche, Jan Van, Angelo, Michael, Bendall, Sean C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7878201/
https://www.ncbi.nlm.nih.gov/pubmed/32868913
http://dx.doi.org/10.1038/s41587-020-0651-8