Cargando…

Leptin Contributes to Neuropathic Pain via Extrasynaptic NMDAR-nNOS Activation

Leptin is an adipocytokine that is primarily secreted by white adipose tissue, and it contributes to the pathogenesis of neuropathic pain in collaboration with N-methyl-D-aspartate receptors (NMDARs). Functional NMDARs are a heteromeric complex that primarily comprise two NR1 subunits and two NR2 su...

Descripción completa

Detalles Bibliográficos
Autores principales: Liang, Yanling, Ma, Yuxin, Wang, Jieqin, Nie, Lei, Hou, Xusheng, Wu, Wenyu, Zhang, Xingmei, Tian, Yinghong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer US 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7878206/
https://www.ncbi.nlm.nih.gov/pubmed/33099751
http://dx.doi.org/10.1007/s12035-020-02180-1