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Leptin Contributes to Neuropathic Pain via Extrasynaptic NMDAR-nNOS Activation
Leptin is an adipocytokine that is primarily secreted by white adipose tissue, and it contributes to the pathogenesis of neuropathic pain in collaboration with N-methyl-D-aspartate receptors (NMDARs). Functional NMDARs are a heteromeric complex that primarily comprise two NR1 subunits and two NR2 su...
| Autores principales: | , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Springer US
2020
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7878206/ https://www.ncbi.nlm.nih.gov/pubmed/33099751 http://dx.doi.org/10.1007/s12035-020-02180-1 |