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Epineural optogenetic activation of nociceptors initiates and amplifies inflammation

Activation of nociceptor sensory neurons by noxious stimuli both triggers pain and increases capillary permeability and blood flow to produce neurogenic inflammation(1,2), but whether nociceptors also interact with the immune system remains poorly understood. Here we report a neurotechnology for sel...

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Detalles Bibliográficos
Autores principales: Michoud, Frédéric, Seehus, Corey, Schönle, Philipp, Brun, Noé, Taub, Daniel, Zhang, Zihe, Jain, Aakanksha, Furfaro, Ivan, Akouissi, Outman, Moon, Rachel, Meier, Pascale, Galan, Katia, Doyle, Benjamin, Tetreault, Michael, Talbot, Sébastien, Browne, Liam E., Huang, Qiuting, Woolf, Clifford J., Lacour, Stéphanie P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7878280/
https://www.ncbi.nlm.nih.gov/pubmed/32958958
http://dx.doi.org/10.1038/s41587-020-0673-2