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The Threshold Effect: Lipopolysaccharide-Induced Inflammatory Responses in Primary Macrophages Are Differentially Regulated in an iRhom2-Dependent Manner

A well-controlled innate immune response is characterized by a rapid yet self-limiting inflammatory response. Although much is known about the range of inflammatory stimuli capable of triggering an innate immune response, the mechanisms which govern the degree of inflammation induced by inflammatory...

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Detalles Bibliográficos
Autores principales: Skurski, Joseph, Dixit, Garima, Blobel, Carl P., Issuree, Priya D., Maretzky, Thorsten
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7878383/
https://www.ncbi.nlm.nih.gov/pubmed/33585287
http://dx.doi.org/10.3389/fcimb.2020.620392