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Self-assembly and regulation of protein cages from pre-organised coiled-coil modules
Coiled-coil protein origami (CCPO) is a modular strategy for the de novo design of polypeptide nanostructures. CCPO folds are defined by the sequential order of concatenated orthogonal coiled-coil (CC) dimer-forming peptides, where a single-chain protein is programmed to fold into a polyhedral cage....
Autores principales: | Lapenta, Fabio, Aupič, Jana, Vezzoli, Marco, Strmšek, Žiga, Da Vela, Stefano, Svergun, Dmitri I., Carazo, José María, Melero, Roberto, Jerala, Roman |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7878516/ https://www.ncbi.nlm.nih.gov/pubmed/33574245 http://dx.doi.org/10.1038/s41467-021-21184-6 |
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