In vitro model of perimenopausal depression implicates steroid metabolic and proinflammatory genes

The estimated 20–30% of women who develop perimenopausal depression (PMD) are at an increased risk of cardiovascular and all-cause mortality. The therapeutic benefits of estradiol (E2) and symptom-provoking effects of E2-withdrawal (E2-WD) suggest that a greater sensitivity to changes in E2 at the c...

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Detalles Bibliográficos
Autores principales: Rudzinskas, Sarah, Hoffman, Jessica F., Martinez, Pedro, Rubinow, David R., Schmidt, Peter J., Goldman, David
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7878574/
https://www.ncbi.nlm.nih.gov/pubmed/32788687
http://dx.doi.org/10.1038/s41380-020-00860-x

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7878574/
https://www.ncbi.nlm.nih.gov/pubmed/32788687
http://dx.doi.org/10.1038/s41380-020-00860-x

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