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Stabilization of the Hinge Region of Human E-selectin Enhances Binding Affinity to Ligands Under Force
INTRODUCTION: E-selectin is a member of the selectin family of cell adhesion molecules expressed on the plasma membrane of inflamed endothelium and facilitates initial leukocyte tethering and subsequent cell rolling during the early stages of the inflammatory response via binding to glycoproteins ex...
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer International Publishing
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7878631/ https://www.ncbi.nlm.nih.gov/pubmed/33633813 http://dx.doi.org/10.1007/s12195-021-00666-z |