The neurorepellent, Slit2, prevents macrophage lipid loading by inhibiting CD36-dependent binding and internalization of oxidized low-density lipoprotein

Atherosclerosis is characterized by retention of modified lipoproteins, especially oxidized low density lipoprotein (oxLDL) within the sub-endothelial space of affected blood vessels. Recruited monocyte-derived and tissue-resident macrophages subsequently ingest oxLDL by binding and internalizing ox...

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Detalles Bibliográficos
Autores principales: Yusuf, Bushra, Mukovozov, Ilya, Patel, Sajedabanu, Huang, Yi-Wei, Liu, Guang Ying, Reddy, Emily C., Skrtic, Marko, Glogauer, Michael, Robinson, Lisa A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7878733/
https://www.ncbi.nlm.nih.gov/pubmed/33574432
http://dx.doi.org/10.1038/s41598-021-83046-x

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7878733/
https://www.ncbi.nlm.nih.gov/pubmed/33574432
http://dx.doi.org/10.1038/s41598-021-83046-x

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