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Convergence of biomarkers and risk factor trait loci of coronary artery disease at 3p21.31 and HLA region

Here we seek to identify molecular biomarkers that mediate the effect of risk factors on coronary artery disease (CAD). We perform a SNP-based multiomics data analysis to find biomarkers (probes) causally associated with the risk of CAD within known genomic loci for its risk factors. We identify 78...

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Detalles Bibliográficos
Autores principales: Nikpay, Majid, McPherson, Ruth
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7878768/
https://www.ncbi.nlm.nih.gov/pubmed/33574266
http://dx.doi.org/10.1038/s41525-021-00174-z