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Cell-to-Cell Adhesion and Neurogenesis in Human Cortical Development: A Study Comparing 2D Monolayers with 3D Organoid Cultures
Organoids (ORGs) are increasingly used as models of cerebral cortical development. Here, we compared transcriptome and cellular phenotypes between telencephalic ORGs and monolayers (MONs) generated in parallel from three biologically distinct induced pluripotent stem cell (iPSC) lines. Multiple read...
Autores principales: | Scuderi, Soraya, Altobelli, Giovanna G., Cimini, Vincenzo, Coppola, Gianfilippo, Vaccarino, Flora M. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7878838/ https://www.ncbi.nlm.nih.gov/pubmed/33513360 http://dx.doi.org/10.1016/j.stemcr.2020.12.019 |
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