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The molecular conformation of silk fibroin regulates osteogenic cell behavior by modulating the stability of the adsorbed protein-material interface

Silk fibroin (SF) can be used to construct various stiff material interfaces to support bone formation. An essential preparatory step is to partially transform SF molecules from random coils to β-sheets to render the material water insoluble. However, the influence of the SF conformation on osteogen...

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Detalles Bibliográficos
Autores principales: Long, Yanlin, Cheng, Xian, Jansen, John A., Leeuwenburgh, Sander G. C., Mao, Jing, Yang, Fang, Chen, Lili
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7878842/
https://www.ncbi.nlm.nih.gov/pubmed/33574222
http://dx.doi.org/10.1038/s41413-020-00130-0