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The molecular conformation of silk fibroin regulates osteogenic cell behavior by modulating the stability of the adsorbed protein-material interface
Silk fibroin (SF) can be used to construct various stiff material interfaces to support bone formation. An essential preparatory step is to partially transform SF molecules from random coils to β-sheets to render the material water insoluble. However, the influence of the SF conformation on osteogen...
Autores principales: | Long, Yanlin, Cheng, Xian, Jansen, John A., Leeuwenburgh, Sander G. C., Mao, Jing, Yang, Fang, Chen, Lili |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7878842/ https://www.ncbi.nlm.nih.gov/pubmed/33574222 http://dx.doi.org/10.1038/s41413-020-00130-0 |
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